One area of our practice at Siragusa Vein and Laser that is always a top priority is ensuring our patients have the best experience possible. We strive to not only deliver the best care and results, but also make our patient’s experience as comfortable and stress-free as possible. One example of how we carry out this commitment is our use of ProNox™ Nitrous Oxide Delivery System.

What Is Pronox®?

ProNox® is an innovative system that uses a patient-controlled, 50/50 combination of nitrous oxide and oxygen to minimize anxiety and discomfort from any procedure that is performed under local anesthesia. Nitrous oxide is a common sedative (often known as laughing gas) that calms the central nervous system, allowing patients to feel comfortable during their treatment.

How Is Pronox® Administered?

Besides the calming, relaxing effects of Pronox, patients love that they are in control of the sedative. Patients simply breath through a small hose or tube supplying the nitrous oxide and oxygen, so they can use as much or as little as they want during their treatment. It is as simple as breathing through a straw. With Pronox, your comfort and relaxation is at your fingertips and only a few breaths away.

Will I Feel Anything During The Procedure?

ProNox® is not a replacement for a local anesthetic, although nitrous oxide does have an analgesic effect. When a patient uses ProNox®, the responsiveness of the central nervous system slows down. This works in combination with the local anesthetics we use, such as lidocaine, to maximize patient comfort. Unlike general anesthesia, Pronox does not put patients “to sleep”. This allows patients to experience the calming benefits while also allowing for communication with our staff during treatment to help manage comfort levels. Following treatment, patients who have opted to use Pronox are free to resume their daily activities, including driving, as the Pronox wears off within 5 minutes of administration.


  • Conservative Vein Treatment

  • Endovenous Ablation

  • EVLT

  • Phlebectomy

  • Pronox

  • Radiofrequency Ablation

  • Sclerotherapy

  • Ultrasound Guided Foam Sclerotherapy

  • Varithena

Take The First Step

If you have any anxiety regarding your treatment, please ask us for more information on how Pronox can help make your experience at Siragusa Vein and Laser as comfortable as possible.